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The DOPPS is a prospective cohort study of hemodialysis practices based on the collection of observational longitudinal
data for a random sample of patients from a representative and random sample of units in 12 countries
(Australia, Belgium, Canada, France, Germany, Japan, Italy, New Zealand, Spain, Sweden, the United Kingdom, and the United States).
Data collection for the study has been on-going since 1996 and has yielded detailed data on more than 38,000 patients in over 900
dialysis facilities.
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DOPPS investigations focus on determining which dialysis practices are associated with the best patient outcomes,
with the primary goal
of improving patient longevity, quality of life, and other outcomes. With over 75 peer-reviewed publications in
print or in press, the DOPPS continues to provide numerous important findings that are relevant for patients and practicing clinicians
alike. The DOPPS is supported by scientific research grants from Amgen (since 1996), Kyowa Hakko Kirin (since 1999, in Japan), Genzyme
(since 2009), and Abbott (since 2009) without restrictions on publications.
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Arbor Research and DOPPS are proud to announce the release of the 2009 DOPPS Annual Report.
The DOPPS Annual Report is a comprehensive collection of descriptive statistics spanning more than a
decade of longitudinal DOPPS data collection. Calculated for multiple, representative cross-sectional
cohorts, each Annual Report portrays country-specific results and illustrates trends over several
practice areas. The Annual Report also includes a summary of DOPPS study design and methods used in
calculating the results for the Annual Report.
The symposium is entitled “Modifiable hemodialysis practices: latest trends and outcomes from the DOPPS".
The session will be chaired by Dr. Bruce Robinson and features an international panel of speakers from
DOPPS. The program will take a critical look at modifiable practices in areas such as cardiovascular
disease, anemia and MBD management. The program will highlight the study’s most recent clinical findings.
Additionally, nine DOPPS abstract presentations will be given, on subjects including anemia management,
mineral bone disease, and many others. Please see our brochure
for further details and a complete listing of DOPPS events occurring at ASN this year.
DOPPS officially entered its fourth study phase with the launch of DOPPS 4 in early 2009.
Scheduled to continue through 2011, DOPPS 4 will utilize a streamlined set of revised data collection
instruments to focus on targeted research areas that could not be addressed with the data from earlier
phases of the study. Much research emphasis for DOPPS 4 is placed on examining the effects of new
changes in hemodialysis treatment, clinical practice guidelines, and health policy. An important
operational enhancement in DOPPS 4 is the addition of the Task Forces, which are groups of experts
who will guide the DOPPS research agenda and questionnaire content in high-priority areas such as
cardiovascular disease, mineral bone disease, and anemia. For a more detailed summary about the new
phase of DOPPS, please see this bulletin.
Also, several study design and process highlights about DOPPS 4 are described in our promotional pamphlet.
New research from the DOPPS was presented during a clinical symposium at WCN 2009,
the joint meeting between ERA-EDTA and ISN. The well-attended symposium, chaired by
Dr. Friedrich Port and Dr. Jorge Andia-Cannata, featured recent results from the DOPPS
and Cosmos. Presentations focused on clinical practice indicators at the dialysis facility
level and associated outcomes with consideration of patient mix. The international perspectives
of DOPPS were emphasized. Additionally, eight abstract presentations were given, including
one oral presentation.
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The DOPPS has published more than 60 papers in peer-reviewed medical journals,
as well as numerous articles in textbooks and other forums.
See our Publications section for detail on the full range of DOPPS publications.
DOPPS Vascular Access Mortality Paper Published
Facility-based analyses diminish treatment-by-indication bias and suggest that less catheter and graft use improves patient survival.
More...
DOPPS Vitamin D Survival Advantage Paper Published
The association between vitamin D and mortality among DOPPS participants is assessed using standard regression
and marginal structural models with an expanded set of covariates, as well as by instrumental variable models to
account for potential bias due to unmeasured confounders. Based on route of vitamin D administration, no difference
in mortality is observed.
More...
DOPPS Practice-Related Risk Score (PRS) Paper Published
The PRS assesses modifiable hemodialysis practices that are linked to improved patient survival.
More...
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Coordinated by research scientists
and staff of Arbor Research Collaborative
for Health, and supported by research grants from Amgen (since 1996),
Kyowa Hakko Kirin (since 1999, in Japan), Genzyme (since 2009), and Abbott (since 2009) without
restrictions on publications.
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The DOPPS Annual Report
The DOPPS Annual Report portrays descriptive statistics for multiple, representative cross-sectional cohorts over several practice areas, from anemia to vascular access.
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DOPPS Presentations of Published Research
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