Dialysis and Advanced CKD Outcomes and Practice Patterns Study Program

The DOPPS is a collection of studies designed to identify best practices for treating patients with chronic kidney failure. Started as a hemodialysis study in 1996, the DOPPS now tracks over 70,000 patients on hemodialysis, peritoneal dialysis, and with chronic kidney disease, in over 20 countries. By observing patients over time, and correlating practices and outcomes in different medical settings around the world, the DOPPS helps researchers identify practices and other modifiable characteristics that improve patient lives.

What Does the DOPPS Study?

Practice Patterns
Approaches to treatment chosen by medical providers, such as:
  • Staff per patient
  • Types and skills of staff
  • Number of patients served
  • Vascular access creation and salvage policies
  • Dialysis “dose” and other prescriptions
  • Methods of delivering dialysis and achieving dose
  • Decisions about starting dialysis
 
 
 
Outcomes
Important outcomes assessed in DOPPS include:
  • Mortality
  • Hospitalization
  • Infections
  • Vascular access failure
  • Quality of life
  • Development of new medical condition

 

What is Different about Our Approach?

Longitudinal

The DOPPS is longitudinal and collects information on hemodialysis centers and patients in more than twenty countries using a common protocol over time. With a focus on the full range of unit practice patterns that may relate to clinically important outcomes, the outcomes measures will be adjusted for patient comorbidities and adjusted to a greater extent than previously possible in other studies.

International

The international scope of the DOPPS provides greater variability in practice patterns and outcomes than can be observed in one country. This increased variation along with the study's large sample size leads to a greatly enhanced ability to understand the relationships between various treatment effects and patient outcomes.

The efforts of the DOPPS to obtain a representative, random sample of facilities and patients within each country allows for practice patterns within a participating country to be described.

A detailed protocol of more than 1,000 data fields, repeated across time and geography

Data Elements/Collection: Common protocol of 1,000 questions

  • Patient-Level Data – includes comorbidities; hospitalizations; detailed monthly laboratory, treatment, and & medication data
  • Medical Director and Facility Unit Practice surveys
  • Patient Self-Reported Survey